FDA Approves First Drug To Boost Women's Sexual Desire

But, for now, it appears safe to use a pill or supplement to promote potential long-term benefits while also using female arousal topicals for an extra, more timely boost.

• [Intrinsa: Testosterone patch for surgically menopausal women.]
• [AndroFeme: Testosterone cream for women.]
• [Divigel: Estrogen gel, can help vaginal health.]
• [Premarin: Conjugated estrogens for menopausal symptoms.]
• [Vagifem: Estrogen tablet for vaginal atrophy.]

L-Arginine, L-citrulline, and L-carnitine may improve blood flow to the genitalia Zinc and magnesium could help physical arousal in people with deficiencies Capsules are vegan-friendly (corn- and plant-based gelatin) Ingredients should be generally safe for most people 60-day money-back guarantee for new customers Subscribe for 15% off of recurring deliveries Save $5 when you visit Promescent using our links on this page Unsafe for pregnant or breastfeeding individuals and those with corn allergies Dose is six capsules daily (three pills, twice a day) L-arginine may trigger a herpes flare-up Promescent made its name by pioneering delay sprays to help men overcome premature ejaculation, but the company has since greatly expanded its catalog of sexual health products.

• [Cialis (Tadalafil): Off-label use for female sexual arousal.]
• [Levitra (Vardenafil): Another PDE5 inhibitor used off-label.]
• [Stendra (Avanafil): PDE5 inhibitor, potential off-label use.]
• [Muse (Alprostadil): Urethral suppository, primarily for men.]
• [Caverject (Alprostadil): Injection, primarily for men.]

Its VitaFLUX supplement is available for men and women (both are the exact same except for label color), but in this guide, we'll focus on what this supplement might do for those with female anatomy. Promescent claims VitaFLUX for Women may help: Aid in faster recovery from injury or exhaustion We’ll investigate the validity of these claims next, but it seems like Promescent intends for VitaFLUX to boost both sexual and overall wellness. This is similar to how Leading Edge Health — the company behind HerSolution — markets its female libido supplements. Before delving into the supplement’s potential efficacy, let’s first take a quick look at the active ingredients in VitaFLUX, which include: Though it has more of them, VitaFLUX isn’t the only product in this guide to use amino acids to support sexual health. For example, both Jolt Gel (a topical) and Hello Cake’s Drive For Her (a supplement) also contain L-arginine.

Now, let’s break down how (or if) these ingredients can potentially provide the benefits suggested by Promescent. A systematic review of research studies suggests that L-arginine (along with L-citrulline) can result in greater sexual arousal and satisfaction for pre-, peri-, and postmenopausal women who have HSDD or a related concern. The effective daily dosages that led to promising results within the examined studies were similar to the arginine dose delivered daily by VitaFLUX.10 These positive results are likely due to the fact that L-arginine is a precursor of nitric oxide (NO), which promotes better blood flow throughout the body (including to the genitals). Nitric oxide is also believed to play a major role in the smooth muscle relaxation of sexual arousal.14 Additionally, the increase in blood circulation from nitric oxide’s vasodilation properties can reduce vaginal dryness, as vaginal lubrication is actually ultra-filtered blood.19 L-Citrulline is partially converted to L-arginine, which is then converted to nitric oxide, meaning that this amino acid can also promote NO production.10 Research on L-citrulline for sexual dysfunction usually involves it being used with L-arginine, and most of the research on L-citrulline alone involves men. For example, one study found that 1.5g (1,500mg) of L-citrulline appears to be a safe and effective alternative treatment for mild to moderate erectile dysfunction.20 However, since researchers note that this outcome is likely due to increased NO production, it can be assumed that women may also experience similar benefits from L-citrulline. L-Carnitine is an amino acid that plays a critical role in energy production — it transports fatty acids to the mitochondria (that “powerhouse of the cell” you likely heard about in science class) to be turned into a form of energy called adenosine triphosphate (ATP).21 This amino acid also shows the potential to improve exercise performance while reducing oxidative stress in response to resistance training.22 This could be why Promescent states that VitaFLUX may be able to help you recover more quickly from injury or exhaustion. And, while there isn’t much research on L-carnitine and sexual function, one study on lambs found that “a disruption in carnitine homeostasis” led to a reduction in bioavailable NO. In this study, maintaining carnitine homeostasis kept ATP levels adequate, which also appeared to have a positive effect on preserving Hsp90 activity. This “molecular chaperone” can help support hormone signaling pathways (such as those for estrogen and testosterone).23 The research on magnesium and sexual function is sparse, but there is definitely some potential for it to be a beneficial addition.

• [Vivelle-Dot: Estrogen transdermal patch.]
• [Menest: Esterified estrogens tablet.]
• [Activella: Estradiol/norethindrone for menopause.]
• [Premphase: Conjugated estrogens/medroxyprogesterone.]
• [Prefest: Estradiol/norgestimate combination pill.]

One study on the magnesium levels of men reporting premature ejaculation (PE) found that lower levels were “significantly related” to the condition.24 However, more research is needed on the relationship between magnesium and PE. A separate study on the role magnesium plays in hypertension and cardiovascular disease has information that’s actually more closely related to the potential benefits for female sexual dysfunction than the other study. Researchers note that the mineral mimics the effects of a calcium channel blocker — a drug for lowering blood pressure that allows “blood vessels to relax and open.” This results in increased nitric oxide production and improved blood flow, similar to the amino acids in the VitaFLUX formula.25 26 A study from 2021 found that zinc supplementation for postmenopausal women whose serum zinc levels were low resulted in dramatic improvements in desire for sex and sexual pleasure; vaginal lubrication improved, while pain diminished. This may be due to the resulting increase in testosterone found by the researchers.27 Additionally, one study on zinc and nitric oxide notes that both are heavily involved in the various signal transduction pathways of the body, describing them as “intersecting.”28 As with all treatments, VitaFLUX may not work for everyone or provide the same potential benefits to everyone. If this supplement is right for you and your body, you’ll likely start to see some improvements after around a month or so. If there are no noticeable changes whatsoever after your first bottle is gone (30 days of use), then it may be time to try something else. The ingredients in VitaFLUX fall well below established tolerable upper limits, so the product should generally be safe for most healthy adults. Side effects of amino acids at the doses present in this supplement are more likely to be mild and may include libido booster for woman gastrointestinal upset (like nausea and diarrhea).61 However, we always recommend speaking with your doctor before trying a new supplement to make sure it’s a safe choice for you.

Lifestyle and home remedies

Unlike the prescriptions Addyi and Vyleesi, sildenafil isn’t FDA-approved for the treatment of any female sexual dysfunction (FSD) concerns, so the use of the drug in OMG! In comparison to the wait it takes for supplements to work (weeks to months), topicals like OMG! Cream should take effect within an hour of application. Cream, after checkout you’ll be prompted to verify your identity and complete a quick telehealth visit. The list below details some particular instances where VitaFLUX may not be ideal: Taking L-arginine could trigger a herpes flare-up (both HSV-1 and HSV-2).3 L-carnitine can possibly interact with some medications: doxorubicin, thyroid hormones, and blood thinners.4 Due to nitric oxide's vasodilating effects, this product might not be safe for people taking certain medications, such as those for blood pressure.63 Zinc may interact with antibiotics, penicillamine, and thiazide diuretics.29 Although the zinc content is far below the tolerable upper limit for adults (40mg daily), be careful not to over-supplement if you take another supplement containing zinc.

Exceeding the upper limit of zinc for an extended period of time is unsafe and could lead to a deficit of copper in your body, among other things.30 Also, individuals who are pregnant or breastfeeding should avoid taking VitaFLUX. Promescent used to sell VitaFLUX for Women in both capsule and powder form, but the latter seems to have been discontinued since we last checked in with the company.

Natural Ways to Increase Libido

Pivoting back to VitaFLUX, you can purchase this supplement as either a single bottle or a bulk pack of three. Both options are available as single purchases or subscriptions. The chart below breaks down the details. (The single purchase pricing includes our $5 off discount.) If you prefer shopping on Amazon, you can find VitaFLUX there as well, but it appears to mainly be sold by third-party sellers (not Promescent or Amazon) so the quality — and authenticity — of the product can’t always be guaranteed. You also won’t be able to use our $5 discount or subscribe for 15% off of recurring deliveries.

Sorry something went wrong with your subscription

Additionally, shipping from Promescent is free for orders over $20, meaning that any VitaFLUX purchase qualifies. Finally, if you’re unsatisfied with your purchase from Promescent, VitaFLUX qualifies for the company’s 60-day money-back guarantee. However, this offer is only valid for new customers or existing customers trying the product for the first time. This guarantee is fairly generous, and it’s about the same length as the one for HerSolution (67 days). Prescription is customized based on your unique case Topical sildenafil has shown promise in a clinical study Subscriptions can reduce costs and auto-ship you one or two bottles per quarter Telehealth visit is included in the purchase price Not safe for pregnant individuals; pentoxifylline can harm your baby Doesn’t treat underlying cause of sexual dysfunction Cream, from the sexual-health-focused telehealth platform Wisp, is a prescription topical arousal gel that’s compounded according to the information you provide during your virtual visit. Unfortunately, this means that those who dislike the idea of taking six capsules daily — or those who simply can’t swallow pills — may need to look elsewhere. This could mean trying topicals, like Wisp’s OMG! Cream, or something like Cake’s Libido Lift Rx, which is a sublingual tablet that dissolves under your tongue.

Pivoting back to VitaFLUX, you can purchase this supplement as either a single bottle or a bulk pack of three. Both options are available as single purchases or subscriptions. The chart below breaks down the details. (The single purchase pricing includes our $5 off discount.) If you prefer shopping on Amazon, you can find VitaFLUX there as well, but it appears to mainly be sold by third-party sellers (not Promescent or Amazon) so the quality — and authenticity — of the product can’t always be guaranteed. You also won’t be able to use our $5 discount or subscribe for 15% off of recurring deliveries.

Episode Transcript

This “molecular chaperone” can help support hormone signaling pathways (such as those for estrogen and testosterone).23 The research on magnesium and sexual function is sparse, but there is definitely some potential for it to be a beneficial addition. One study on the magnesium levels of men reporting premature ejaculation (PE) found that lower levels were “significantly related” to the condition.24 However, more research is needed on the relationship between magnesium and PE. A separate study on the role magnesium plays in hypertension and cardiovascular disease has information that’s actually more closely related to the potential benefits for female sexual dysfunction than the other study. Researchers note that the mineral mimics the effects of a calcium channel blocker — a drug for lowering blood pressure that allows “blood vessels to relax and open.” This results in increased nitric oxide production and improved blood flow, similar to the amino acids in the VitaFLUX formula.25 26 A study from 2021 found that zinc supplementation for postmenopausal women whose serum zinc levels were low resulted in dramatic improvements in desire for sex and sexual pleasure; vaginal lubrication improved, while pain diminished. This may be due to the resulting increase in testosterone found by the researchers.27 Additionally, one study on zinc and nitric oxide notes that both are heavily involved in the various signal transduction pathways of the body, describing them as “intersecting.”28 As with all treatments, VitaFLUX may not work for everyone or provide the same potential benefits to everyone.

What causes a decrease in female libido?

If this supplement is right for you and your body, you’ll likely start to see some improvements after around a month or so. If there are no noticeable changes whatsoever after your first bottle is gone (30 days of use), then it may be time to try something else. The ingredients in VitaFLUX fall well below established tolerable upper limits, so the product should generally be safe for most healthy adults. Side effects of amino acids at the doses present in this supplement are more likely to be mild and may include libido booster for woman gastrointestinal upset (like nausea and diarrhea).61 However, we always recommend speaking with your doctor before trying a new supplement to make sure it’s a safe choice for you. The list below details some particular instances where VitaFLUX may not be ideal: Taking L-arginine could trigger a herpes flare-up (both HSV-1 and HSV-2).3 L-carnitine can possibly interact with some medications: doxorubicin, thyroid hormones, and blood thinners.4 Due to nitric oxide's vasodilating effects, this product might not be safe for people taking certain medications, such as those for blood pressure.63 Zinc may interact with antibiotics, penicillamine, and thiazide diuretics.29 Although the zinc content is far below the tolerable upper limit for adults (40mg daily), be careful not to over-supplement if you take another supplement containing zinc.

Rx Vaginal Creams

Exceeding the upper limit of zinc for an extended period of time is unsafe and could lead to a deficit of copper in your body, among other things.30 Also, individuals who are pregnant or breastfeeding should avoid taking VitaFLUX. Promescent used to sell VitaFLUX for Women in both capsule and powder form, but the latter seems to have been discontinued since we last checked in with the company. Unfortunately, this means that those who dislike the idea of taking six capsules daily — or those who simply can’t swallow pills — may need to look elsewhere. This could mean trying topicals, like Wisp’s OMG! Cream, or something like Cake’s Libido Lift Rx, which is a sublingual tablet that dissolves under your tongue. Additionally, shipping from Promescent is free for orders over $20, meaning that any VitaFLUX purchase qualifies.

• [Magnet Therapy Pills: Placebo pills claiming energetic benefits.]
• [Homeopathic Libido Pills: Highly diluted substances.]
• [Libigirl: Herbal supplement blend for women.]
• [VigorUp for Women: Contains tribulus and other herbs.]
• [HerSolution: Herbal supplement marketed for arousal.]

Finally, if you’re unsatisfied with your purchase from Promescent, VitaFLUX qualifies for the company’s 60-day money-back guarantee. However, this offer is only valid for new customers or existing customers trying the product for the first time. This guarantee is fairly generous, and it’s about the same length as the one for HerSolution (67 days). Prescription is customized based on your unique case Topical sildenafil has shown promise in a clinical study Subscriptions can reduce costs and auto-ship you one or two bottles per quarter Telehealth visit is included in the purchase price Not safe for pregnant individuals; pentoxifylline can harm your baby Doesn’t treat underlying cause of sexual dysfunction Cream, from the sexual-health-focused telehealth platform Wisp, is a prescription topical arousal gel that’s compounded according to the information you provide during your virtual visit. Unlike the prescriptions Addyi and Vyleesi, sildenafil isn’t FDA-approved for the treatment of any female sexual dysfunction (FSD) concerns, so the use of the drug in OMG! In comparison to the wait it takes for supplements to work (weeks to months), topicals like OMG!

The #1 Prescribed Treatment for frustrating Low Libido1

But, for now, it appears safe to use a pill or supplement to promote potential long-term benefits while also using female arousal topicals for an extra, more timely boost. L-Arginine, L-citrulline, and L-carnitine may improve blood flow to the genitalia Zinc and magnesium could help physical arousal in people with deficiencies Capsules are vegan-friendly (corn- and plant-based gelatin) Ingredients should be generally safe for most people 60-day money-back guarantee for new customers Subscribe for 15% off of recurring deliveries Save $5 when you visit Promescent using our links on this page Unsafe for pregnant or breastfeeding individuals and those with corn allergies Dose is six capsules daily (three pills, twice a day) L-arginine may trigger a herpes flare-up Promescent made its name by pioneering delay sprays to help men overcome premature ejaculation, but the company has since greatly expanded its catalog of sexual health products. Its VitaFLUX supplement is available for men and women (both are the exact same except for label color), but in this guide, we'll focus on what this supplement might do for those with female anatomy. Promescent claims VitaFLUX for Women may help: Aid in faster recovery from injury or exhaustion We’ll investigate the validity of these claims next, but it seems like Promescent intends for VitaFLUX to boost both sexual and overall wellness. This is similar to how Leading Edge Health — the company behind HerSolution — markets its female libido supplements.

IN CLINICAL TRIALS1, WOMEN ON ADDYI EXPERIENCED:

Before delving into the supplement’s potential efficacy, let’s first take a quick look at the active ingredients in VitaFLUX, which include: Though it has more of them, VitaFLUX isn’t the only product in this guide to use amino acids to support sexual health. For example, both Jolt Gel (a topical) and Hello Cake’s Drive For Her (a supplement) also contain L-arginine. Now, let’s break down how (or if) these ingredients can potentially provide the benefits suggested by Promescent. A systematic review of research studies suggests that L-arginine (along with L-citrulline) can result in greater sexual arousal and satisfaction for pre-, peri-, and postmenopausal women who have HSDD or a related concern. The effective daily dosages that led to promising results within the examined studies were similar to the arginine dose delivered daily by VitaFLUX.10 These positive results are likely due to the fact that L-arginine is a precursor of nitric oxide (NO), which promotes better blood flow throughout the body (including to the genitals).

A note about sex and gender

Nitric oxide is also believed to play a major role in the smooth muscle relaxation of sexual arousal.14 Additionally, the increase in blood circulation from nitric oxide’s vasodilation properties can reduce vaginal dryness, as vaginal lubrication is actually ultra-filtered blood.19 L-Citrulline is partially converted to L-arginine, which is then converted to nitric oxide, meaning that this amino acid can also promote NO production.10 Research on L-citrulline for sexual dysfunction usually involves it being used with L-arginine, and most of the research on L-citrulline alone involves men. For example, one study found that 1.5g (1,500mg) of L-citrulline appears to be a safe and effective alternative treatment for mild to moderate erectile dysfunction.20 However, since researchers note that this outcome is likely due to increased NO production, it can be assumed that women may also experience similar benefits from L-citrulline. L-Carnitine is an amino acid that plays a critical role in energy production — it transports fatty acids to the mitochondria (that “powerhouse of the cell” you likely heard about in science class) to be turned into a form of energy called adenosine triphosphate (ATP).21 This amino acid also shows the potential to improve exercise performance while reducing oxidative stress in response to resistance training.22 This could be why Promescent states that VitaFLUX may be able to help you recover more quickly from injury or exhaustion. And, while there isn’t much research on L-carnitine and sexual function, one study on lambs found that “a disruption in carnitine homeostasis” led to a reduction in bioavailable NO. In this study, maintaining carnitine homeostasis kept ATP levels adequate, which also appeared to have a positive effect on preserving Hsp90 activity. Cream should take effect within an hour of application. Cream, after checkout you’ll be prompted to verify your identity and complete a quick telehealth visit.