
Always talk to your doctor about the risks and benefits of any treatment.
This survey is being conducted by the WebMD marketing sciences department. Applies to the following strengths: 2.5 mg; 5 mg; 10 mg; 20 mg Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity. Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability. Maximum dose: 20 mg once a day Initial dose: 5 mg orally once a day Sexual stimulation is required for a response to treatment. A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers.
Patients taking alpha-blockers should not initiate vardenafil therapy with the orally disintegrating tablet. Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity Comments: Sexual stimulation is required for a response to treatment. CrCl: 30 to 80 mL/min: No adjustment recommended. Comment: The orally disintegrating tablet (brand Staxyn) can be used in patients with mild, moderate or severe renal impairment. Mild hepatic vigora spray dysfunction (Child-Pugh A): No adjustment recommended. Learn more about our editorial standards here.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Cialis Generic | 20mg | 60 + 6 Pills | 117.76€ 112.15€ | |
| Cialis Professional | 20mg | 60 + 2 Pills | 183.83€ 175.08€ | |
| Tadalista Super Active | 20mg | 270 + 30 Pills | 661.49€ 629.99€ | |
| Viagra Oral Jelly | 100mg | 30 + 5 Sachets | 115.76€ 110.25€ | |
| Apcalis SX Oral Jelly | 20mg | 10 Sachets | 58.75€ 55.95€ | |
| Kamagra Polo | 100mg | 84 + 4 Pills | 244.49€ 232.85€ | |
| Cialis Original | 20mg | 22 + 2 Pills | 129.20€ 123.05€ | |
| Kamagra Oral Jelly | 100 mg | 90 + 8 Sachets | 303.56€ 289.10€ | |
| Cialis Professional | 40mg | 120 + 4 Pills | 436.68€ 415.89€ | |
| Levitra Generic | 40mg | 60 + 4 Pills | 162.37€ 154.64€ | |
| Cialis Professional | 20mg | 30 Pills | 104.57€ 99.59€ | |
| Cialis Soft Tabs | 20mg | 60 + 4 Pills | 159.37€ 151.78€ | |
| Kamagra Polo | 100mg | 180 + 8 Pills | 446.52€ 425.26€ | |
| Levitra Generic | 20mg | 90 + 8 Pills | 180.78€ 172.17€ | |
| Cialis Generic | 60mg | 90 + 6 Pills | 196.67€ 187.30€ | |
| Cialis Original | 20mg | 92 + 4 Pills | 377.99€ 359.99€ |
All trademarks are the property of their respective owners.
*This information is from the vardenafil hydrochloride label used by Teva Pharmaceuticals USA, Inc. See the Full Prescribing Information for cost of vardenafil more complete information. Vardenafil may be the active ingredient in other medications, and this information may not be accurate for all medications that include the active ingredient vardenafil. This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Use of third-party trademarks is for informational purposes only and does not imply endorsement or affiliation with Hims, Inc. Studies in men with ED have shown that single doses of vardenafil 10–40 mg were rapidly absorbed following oral
Patients treated with alpha-blockers, who have previously used vardenafil film-coated tablets, may be switched to ODT tablets at the advice of their healthcare provider. Patients should stop use of PDE5 inhibitors, including this drug, and seek medical attention in the event of sudden loss of vision in one or both eyes, and decrease or loss of hearing. Symptoms related to postural hypotension may occur, appropriate countermeasures are recommended. Contact the prescribing physician if other antihypertensive drugs or new medications that may interact with this drug are prescribed by another healthcare provider. Patients should contact their healthcare provider for dose modification if they are not satisfied with the quality of their sexual performance with this drug, or in the case of an unwanted side effect.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Vardenafil (Levitra®) is an oral medication for ED that starts working in about 60 minutes and lasts up to five hours. Vardenafil is a medication used to treat erectile dysfunction (ED) by increasing blood flow to the penis during sexual stimulation. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors and works similarly erection tablets to sildenafil (Viagra®) and tadalafil (Cialis®). Vardenafil is typically taken as needed, about 60 minutes before sexual activity, and its effects can last up to five hours. administration, with maximum plasma concentrations (Cmax) reached in some men within 15 minutes (median 0.6–0.9 hours) (Table 2) [4,5].
Most insurance companies will not cover the cost of vardenafil because they don’t consider it medically necessary. Administration with nitrates and nitric oxide donors Administration with nitrates and nitric oxide donors Administration with guanylate cyclase (GC) stimulators, such as riociguat Administration with guanylate cyclase (GC) stimulators, such as riociguat Cardiovascular effects: Patients should not use vardenafil hydrochloride if sex is inadvisable due to cardiovascular status Cardiovascular effects: Patients should not use vardenafil hydrochloride if sex is inadvisable due to cardiovascular status Risk of prolonged erection: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance Risk of prolonged erection: In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance Effects on the eye: Patients should stop use of vardenafil hydrochloride and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION) Effects on the eye: Patients should stop use of vardenafil hydrochloride and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION) Sudden hearing loss: Patients should stop vardenafil hydrochloride and seek medical attention in the event of sudden decrease or loss in hearing Sudden hearing loss: Patients should stop vardenafil hydrochloride and seek medical attention in the event of sudden decrease or loss in hearing Alpha-blockers: Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers Alpha-blockers: Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers QT prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafil hydrochloride QT prolongation: Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using vardenafil hydrochloride The typical vardenafil dose is 10 mg, but the medication is also available in 2.5 mg, 5 mg, and 20 mg doses. Your healthcare provider can help you decide which dose is best for you. Although early clinical trials show that vardenafil is more potent than Viagra’s active ingredient, sildenafil, both medications were deemed similarly effective in treating ED. The half-life of vardenafil is four to five hours, meaning it effectively relieves ED for an average of five hours at a time, but it’s most effective in the first few hours after you’ve taken it. The mean Cmax and area under the plasma concentration time curves (AUC) increased in an almost dose-proportional manner.
Vardenafil orally disintegrating tablets should not be taken with water or liquids. Let it dissolve on your tongue without crushing it. There are no known interactions between vardenafil and alcohol. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. In particular, make sure that you discuss if you are using any of the following before taking vardenafil.
Tell your healthcare provider about all medicines that you take or have recently taken. This may not be a complete list of medicines that can interact with vardenafil. If you or someone else has taken too much vardenafil, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222. Take it as your healthcare provider recommends, which is usually about one hour before planned sexual activity. Do not take double or extra doses. Vardenafil has a mean absolute bioavailability of 15%.
The rate and extent of absorption did not alter when vardenafil 20 mg was administered immediately
after a typical meal (approximately 30% of calories as fat) compared with in the fasting state.
Moderate hepatic dysfunction (Child-Pugh B): 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity. The maximum dose should not exceed 10 mg. Severe hepatic dysfunction (Child-Pugh C): Use should be avoided. Comment: The orally disintegrating tablets should not be used in patients with moderate (Child-Pugh B) or severe (Child-Pugh C) hepatic dysfunction. If taking potent or moderate inhibitors of CYP450 3A4, the dose should be adjusted as follows: Ritonavir: No more than 2.5 mg in a 72-hour period Indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, clarithromycin: No more than 2.5 mg in a 24-hour period Ketoconazole 200 mg daily, itraconazole 200 mg daily, erythromycin: No more than 5 mg in a 24-hour period Safety and efficacy have not been established in patients younger than 18 years.
This drug is not indicated for use in pediatric patients. This drug can be taken with or without food. The 10 mg orally disintegrating tablet (ODT) provides higher systemic exposure and is not interchangeable with the 10 mg film-coated tablets. The ODT tablet should be taken without liquid and immediately upon removal from the blister. Patients who require a lower or higher dose than 10 mg should be prescribed the film-coated tablets. A high-fat meal (57% of calories as fat), however, reduced the rate of absorption with an increase in time to maximum plasma concentration (Tmax) of 1 hour and reduced the Cmax by 18% [6].
| Step | Description | Tips |
|---|---|---|
| Taking the medication | Take orally with a glass of water | Can be taken with or without food |
| Timing before sexual activity | 30-60 minutes prior | Avoid heavy fatty meal initially |
| Duration of effect | Up to 4-5 hours, depending on individual | Be aware of your response |
| Do not exceed prescribed dose | Usually 5 mg per dose, once per day | Overdose risks and side effects |
According to the authors’ personal experience in the use of all three available PDE5 inhibitors, it is wise to suggest to patients to initially
use them with an empty stomach (at least two hours after completion of a meal) to maximise the therapeutic effect and optimise onset time.
Common side effects include headaches, flushing, nasal congestion, and dizziness. It should be used with caution in people with cardiovascular conditions and those taking nitrates. Vardenafil hydrochloride tablets are indicated to treat: Most common adverse reactions reported (≥2% of patients) are: The cost of vardenafil depends on factors such as your insurance plan, the dosage, quantity, and where you buy it. Without insurance, the average cost of vardenafil is between $500 and $1,400 for a 30-day supply. However, coupons or discount cards may be available to bring down the price.